Nucleophosmin protein (npm) mutants, corresponding gene...

Details Nucleophosmin protein (npm) mutants, corresponding gene... Nucleophosmin protein (npm) mutants, corresponding gene...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2585965

The invention relates to new nucleophosmin protein (NPM) mutants, corresponding gene sequences and relative uses thereof for diagnosis, monitoring of minimal residual disease; prognostic evaluation and therapy of the acute myeloid leukaemia (AML).

La présente invention concerne de nouveaux mutants de protéine nucléophosmine (NPM), des séquences géniques correspondantes, ainsi que l'utilisation relative de ceux-ci pour diagnostiquer et contrôler une maladie résiduelle minime, évaluer un pronostic et traiter une leucémie myéloïde aiguë (AML).

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