A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61P 25/00 (2006.01) C07K 16/28 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2371592
Novel compositions are described comprising the combined administration of serum complement proteins with complement-fixing antibodies. The antibodies specifically bind to one or more epitopes of myelin, and complement proteins. These compositions are useful for promoting regrowth, repair, and regeneration of neurons in the CNS of a mammalian subject. The compositions and method can be used following immediate or chronic injury.
L'invention concerne des nouvelles compositions ainsi que l'administration combinée de compléments sériques et d'anticorps fixant lesdits compléments. Les anticorps se lient spécifiquement à un ou plusieurs épitopes de myéline et aux compléments. Ces compositions sont utiles pour favoriser la repousse, la réparation et la régénération des neurones dans le système nerveux central d'un sujet mammifère. Les compositions et la méthode de l'invention peuvent être utilisés immédiatement après une lésion chronique.
Bourque Jason
Dyer Jason K.
Keirstead Hans S.
Steeves John D.
Mbm & Co.
University Of British Columbia
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