Novel chemokine-like polypeptides

Details Novel chemokine-like polypeptides Novel chemokine-like polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/19 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2499483

The present invention discloses open reading frames (ORFs) in human genome encoding for novel chemokines-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.

L'invention concerne des cadres de lecture ouverts (ORF) du génome humain codant de nouveaux polypeptides de type chimiokine, et des réactifs associés comprenant des variants, des mutants et des fragments desdits polypeptides, ainsi que des ligands et des antagonistes dirigés contre ceux-ci. L'invention concerne des méthodes d'identification et de fabrication de ces molécules, pour préparer des compositions pharmaceutiques les contenant, et pour les utiliser dans le diagnostic, la prévention et le traitement de maladies.

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