C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 15/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2497025
The present invention concerns the use of methods and compositions for the treatment of cancer and other hyperproliferative diseases. In certain embodiments, methods are described for the treatment of cancer and/or hyperproliferative diseases by administration of compositions containing at least one platinum complex alone or in combination with a modulator of glutathione. In particular, the methods may be used to treat cisplatin or carboplatin resistant tumor cells.
La présente invention concerne le recours à des méthodes et à des compositions de traitement du cancer ainsi que d'autres maladies hyperprolifératives. Dans certains modes de réalisation, des méthodes sont décrites pour le traitement du cancer et/ou de maladies hyperporlifératives par l'administration de compositions contenant au moins un complexe de platine seul ou en association avec un modulateur de glutathione. En particulier, les méthodes peuvent être utilisées pour traiter les cellules tumorales résistant au cisplatine ou au carboplatine.
Khokhar Abdul R.
Siddik Zahid H.
Board Of Regents The University Of Texas System
Kirby Eades Gale Baker
LandOfFree
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