Antineoplastic combinations with mtor inhibitor, herceptin,...

Details Antineoplastic combinations with mtor inhibitor, herceptin,... Antineoplastic combinations with mtor inhibitor, herceptin,...

A - Human Necessities

61

K

A61K 39/395 (2006.01)

Patent

CA 2626326

A combination of temsirolimus and herceptin in the treatment of cancer is provided. A combination of temsirolimus and HKI-272 is provided. A combination of herceptin and HKI-272 is also provided. Regimens and kits for treatment of metastatic breast cancer, containing herceptin, temsirolimus and/or HKI-272, optionally in combination with other anti-neoplastic agents, or immune modulators are described.

La présente invention concerne une combinaison de temsirolimus et d'herceptine pour le traitement du cancer. L'invention concerne plus particulièrement une combinaison de temsirolimus et de HKI-272. L'invention concerne également une combinaison d'herceptine et de HKI-272. L'invention concerne enfin des schémas posologiques et des nécessaires pour le traitement du cancer du sein métastatique, à base d'herceptine, de temsirolimus et/ou de HKI-272, éventuellement en association avec d'autres antinéoplasiques ou modulateurs immunitaires.

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