Media for clostridium bacterium and processes for obtaining...

Details Media for clostridium bacterium and processes for obtaining... Media for clostridium bacterium and processes for obtaining...

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) C07K 14/33 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2556537

Animal product free (APF) media and processes for the culture and fermentation of botulinum toxin producing Clostridium botulinum bacteria. The botulinum toxin obtained can be used for formulating and compounding botulinum toxin pharmaceutical compositions. The APF media can contain significantly reduced levels of meat or dairy by-products and use non-animal based products instead of the animal-derived products. Preferably, the APF media used are substantially free or free of animal derived products.

L'invention concerne les milieux sans produits d'origine animale (SPOA), et des procédés de culture et de fermentation de bactéries Clostridium botulinum productrices de toxine botulique. La toxine botulique obtenue peut être utilisée pour formuler et préparer des compositions pharmaceutiques de toxine botulique. Les milieux SPOA décrit peuvent présenter des taux sensiblement réduits de sous-produits carnés ou laitiers, et contenir des produits d'origine non animale au lieu des produits d'origine animale. Les milieux SPOA utilisés sont de préférence sensiblement exempts de produits d'origine animale.

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