Process of activating anti-microbial materials

Details Process of activating anti-microbial materials Process of activating anti-microbial materials

A - Human Necessities

01

N

A01N 59/00 (2006.01) A01N 59/16 (2006.01) A61L 27/00 (2006.01) A61L 31/00 (2006.01) C23C 14/00 (2006.01) C23C 14/06 (2006.01) C23C 14/14 (2006.01) C23C 14/58 (2006.01)

Patent

CA 2136454

Anti-microbial coatings and powders and method of forming same on medical devices are provided. The coatings are preferably formed by depositing an anti-microbial biocompatible metal by vapour deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by vapour deposition or altered by mechanical working to produce atomic disorder are also provided. The anti-microbial effect of the coatings or powders may be further activated or enhanced by irradiating with a low linear energy transfer form of radiation such as gamma radiation.

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