Protein and nucleic acid expression systems

Details Protein and nucleic acid expression systems Protein and nucleic acid expression systems

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) C07K 14/195 (2006.01) C12N 15/66 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2454573

Among the inventions disclosed herein are: nucleic acid expression systems for bacteria having an intracytoplasmic membrane system, including, for example, methanotrophic bacteria; recombinant nucleic acid constructs comprising a pmo promoter operably linked to an expressible nucleic acid; cloning vectors suitable for making recombinant nucleic acid constructs and methods for the production of proteins such as membrane proteins.

L'invention concerne des systèmes d'expression d'acides nucléiques pour des bactéries possédant un système membranaire intracytoplasmique, par exemple des bactéries méthanotrophes. L'invention porte également sur des constructions d'acide nucléique recombinant comprenant un promoteur pmo fonctionnellement lié à un acide nucléique susceptible d'être exprimé. L'invention concerne en outre des vecteurs de clonage adaptés à la production de constructions d'acide nucléique recombinant, ainsi que des procédés de production de protéines telles que des protéines membranaires.

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