Salts of phenyl piperazines

Details Salts of phenyl piperazines Salts of phenyl piperazines

C - Chemistry, Metallurgy

07

D

167/223, 260/267

C07D 295/033 (2006.01) A61K 31/495 (2006.01) A61K 31/66 (2006.01) A61K 31/675 (2006.01) C07C 59/255 (2006.01) C07C 229/24 (2006.01) C07C 233/47 (2006.01) C07D 209/18 (2006.01) C07D 233/64 (2006.01) C07D 241/26 (2006.01) C07D 295/02 (2006.01) C07D 295/04 (2006.01) C07D 295/06 (2006.01) C07D 295/08 (2006.01) C07D 295/12 (2006.01) C07F 9/09 (2006.01) C07F 9/38 (2006.01) C07F 9/572 (2006.01) C07F 9/6506 (2006.01)

Patent

CA 2008683

ABSTRACT OF THE DISCLOSURE Salts of phenylpiperazines of formula Image I wherein R represents hydrogen, halogen, trifluoromethyl, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, amino, C1-C6- alkanoylamino or C1-C6-alkanoyloxy in association with acid compounds of the formula Image II wherein X represents a hydrogen atom, a hydroxy group, an amino group, a protected amino group or, together with the hydrogen atom on the carbon, an oxo group and R1 represents hydrogen, a phenyl radical, an indolyl-(3)-methyl radical, an imidazolyl-(4)-methyl radical, a C1-C10-alkyl group or a C1- C10-alkyl group that is substituted by one or two hydroxy groups, a carboxy group, a phosphono group (-PO3H2), a C1-C6- alkoxy group, a mercapto group, a C1-C6-alkylthio group, a phenyl group, a hydroxyphenyl group, a C2-C6-alkanoylamino group or a C1-C6-alkoxycarbonyl group wherein the hydroxy groups present may also be esterified by phosphoric acid.

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