A nucleic acid encoding a g-protein-coupled receptor, and...

Details A nucleic acid encoding a g-protein-coupled receptor, and... A nucleic acid encoding a g-protein-coupled receptor, and...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2466521

Provided herein is a novel and useful G-protein coupled receptor that is involved in signal transduction with respect to inflammation and physiological immunological response. Also provided are methods of using the receptor to screen for molecules that may modulate the activity of the receptor. Such molecules may readily have applications in treating a plethora of inflammation and immunological related diseases and disorders.

La présente invention concerne un nouveau récepteur couplé à la protéine G utile, qui est impliqué dans la transduction du signal en liaison avec l'inflammation et la réponse immunologique physiologique. Cette invention concerne également des procédés d'utilisation de ce récepteur pour cribler des molécules susceptibles de moduler l'activité du récepteur. De telles molécules pourraient avoir rapidement des applications dans le traitement de nombreuses inflammations et de maladies ou de troubles de type immunologique.

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