Conserved neisserial antigens

Details Conserved neisserial antigens Conserved neisserial antigens

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/095 (2006.01) C07K 14/22 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2372235

To ensure maximum cross-strain recognition and reactivity, regions of proteins that are conserved between different Neisserial species, serogroups and strains can be used. The invention provides proteins which comprise stretches of amino acid sequence that are shared across the majority of Neisseria, particularly N. meningitidis and N.gonorrhoeae.

Afin d'assurer une reconnaissance et une réactivité maximum de souches croisées, on peut utiliser des régions de protéines conservées parmi différentes espèces de Neisseria, des sérogroupes et des souches. Cette invention concerne des protéines qui comprennent des fragments de séquence d'acide aminé partagés par la majorité des protéines de Neisseria, en particulier par N. meningitidis et N gonorrhoeae.

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