Process for the manufacture of 5-sulfamoyl-anthranilic acids

C - Chemistry – Metallurgy – 07 – D

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C07D 333/24 (2006.01) C07D 213/38 (2006.01) C07D 307/52 (2006.01) C07D 307/54 (2006.01)

Patent

CA 1042896

Abstract of the Disclosure: A process for the manufacture of sulfamoyl anthranilic acids of the general formula I Image (I) in which Ph is phenyl substituted with 1 or 2 halogen atoms, alkyl groups etherified hydroxy groups, and R is aralkyl, heteroaralkyl or cycloalkyl-alkyl, unsaturated in the aliphatic moiety, including oxygen or sulfur and/or substituted with halogen, alkyl or alkoxy in the aromatic moiety, by reacting carboxylic acids with at least one mol-equivalent of an amine ( R-NH2 ) at a temperature above 120°C.

219264

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