Process for halogenation of .beta.-lactam compounds

Details Process for halogenation of .beta.-lactam compounds Process for halogenation of .beta.-lactam compounds

C - Chemistry, Metallurgy

07

D

260/101.5

C07D 501/59 (2006.01) C07D 513/04 (2006.01)

Patent

CA 1150725

X-5147 Abstract Novel halogenating compounds, derived from triaryl phosphites and chlorine or bromine are employed to convert 7-acylamino-3-hydroxy-3-cephem compounds to 7-acylamino-3-halo-3-cephems and the corresponding C-7 imino halide cephem derivatives. The product 3-halo- 3-cephems are antibiotic compounds or intermediates thereto.

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