Production of antibiotic c-15003 pnd

C - Chemistry – Metallurgy – 12 – P

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195/95, 260/237.

C12P 17/18 (2006.01)

Patent

CA 1142467

Abstract of the Disclosure Antibiotic C-15003 PND of the formula: Image wherein R is H or alkanoyl containing not more than 5 carbon atoms is produced by contacting a maytansinoid compound with a culture broth, inclusive of a processed matter derived therefrom, of a microorganism belonging to one of the genera Streptomyces and Chainia which is able to transform said maytansinoid compound into Antibiotic C-15003 PND. Antibiotic C-15003 PND is useful as antitumor, anti- fungal or antiprotozoal agent.

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