Styrylamidines

Details Styrylamidines Styrylamidines

A - Human Necessities

61

K

260/544.3, 260/5

A61K 31/155 (2006.01)

Patent

CA 1071652

Abstract of the Disclosure Styrylamidines are prepared by treating styryl- sulfonylamidines with base. The styrylamidines are effec- tive in the prevention of aggregation of blood platelets and as analgesics. Compounds of the invention are also useful as anticonvulsants, diuretics and antihypertensive agents. The styrylsulfonylamidines of the invention which serve as precursors to the styrylamidines also have anal- gesic properties. Illustrative of the styrylamidines of the present invention are 4-amino-N-(4-aminostyryl)benza- midine and N-(3,4-dichlorostyryl)acetamidine. An example of a styrylsulfonylamidine is N-(styrylsulfonyl)acetamidine.

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