C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/276.1
C07D 495/04 (2006.01) C07D 333/20 (2006.01)
Patent
CA 1106378
ABSTRACT OF THE DISCLOSURE This invention relates to a process for the prepa- ration of pyridine derivatives of the formulae: Image Image and (I) (II) in which R1 is hydrogen, lower alkyl, a phenyl or aralkyl optionally substituted on the aromatic nucleus with at least a halogen atom or a hydroxy, nitro, amino, cyano, carboxy, alkoxycarbonyl, lower alkyl, lower alkoxy or trifluoromethyl group; R2 is hydrogen or lower alkyl; and R3 is hydrogen or at least a substituent selected from a halogen atom, a hydroxy, lower alkyl and lower alkoxy group, and their pharmaceutically acceptable inorganic or organic acid addition salts. Said compounds have particularly an anti- inflammatory and blood-platelet aggregation inhibiting activity. - 1 -
281824
Ferrand Gerard
Frehel Daniel
Maffrand Jean-Pierre
Goudreau Gage & Associates
Parcor
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