Producing 7-alkoxycarbonyl-6,8-dimethyl-4-...

C - Chemistry – Metallurgy – 07 – D

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260/264.3

C07D 237/32 (2006.01)

Patent

CA 1151648

ABSTRACT A process for producing 7-alkoxycarbonyl-6,8-dimethyl-1-phthalazone- 4-.alpha.-hydroxyacetic acid. This compound can be obtained by hydrolyzing 7- alkoxycarbonyl-6,8-dimethyl-4-(.alpha.-halogeno-.alpha.-substituted methyl)-1-phthalazone with a base. The compound is a useful intermediate in the preparation of 7- alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone, a blood platelet anti-coagulant and phosphodiesterase inhibitor.

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