Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins

Details Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/36 (2006.01) A61K 31/54 (2006.01) A61K 31/545 (2006.01) C07D 279/08 (2006.01) C07D 499/00 (2006.01) C07D 501/04 (2006.01) C07D 501/20 (2006.01) C07D 501/40 (2006.01) C07D 501/46 (2006.01)

Patent

CA 1114808

RAN 4410/118 A b s t r a c t Acyl derivatives of the general formula Image (I) , wherein R represents furyl, thienyl or phenyl optionally substituted by halogen, hydroxy, lower alkoxy or lower alkyl, R1 represents lower alkyl or aminocarbonylmethyl and X represents a group of the formula Image , Image or Image (a) (b) (c) in which one of the two symbols R2 and R3 or R4 and R5 represents hydrogen and the other represents lower alkyl, carboxymethyl or sulphomethyl, as well as salts of said compounds and hydrates of said salts and process for their manufacture. The products have antibiotic, especially bacteri- cidal, activity.

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