Stabilized steroid formulations

Details Stabilized steroid formulations Stabilized steroid formulations

A - Human Necessities

61

K

167/194

A61K 31/57 (2006.01) A61K 8/63 (2006.01) A61K 31/58 (2006.01) A61K 47/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1040534

ABSTRACT This invention describes a stabilized steroid composition comprising from 0.01% to 0.5% by weight of the steroid 9.alpha.-fluoro- 21-chloro-11.beta.,16.alpha.,17.alpha.-trihydroxypregn-4-ene-3,20-dione, 16,17- acetonide, 0.005 to 0.2% by weight of an antioxidant selected from the group consisting of propyl gallate, butylated hydroxy- toluene, butylated hydroxyanisole, sodium bisulfite, sodium metabi- sulfite, and ascorbic acid, and polyethylene glycol or a poly- ethylene glycol ester, said polyethylene glycol or polyethylene glycol ester having a polyethylene glycol molecular weight of from 200 to 7500 and, optionally, including an oleaginous material. This composition is useful in the treatment of various dermatoses.

227942

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