Polymeric immunoregulatory agents

Details Polymeric immunoregulatory agents Polymeric immunoregulatory agents

A - Human Necessities

61

K

167/206, 402/297

A61K 31/785 (2006.01) C08F 8/44 (2006.01) C08F 210/00 (2006.01) C08F 222/04 (2006.01)

Patent

CA 1140852

ABSTRACT OF THE DISCLOSURE The disclosure relates to copolymers of olefin monomers having from 2 to about 4 carbon atoms and .alpha.,.beta. -unsaturated polycarboxylic anhydrides having from 4 to about 6 carbon atoms, having an average molecular weight of from about 300 to about 1500, and derivatized to contain both a half-amide, half- carboxylate salt function and an imide function in which said imide function comprises from about 5% to about 40% of said derivatized function. These copolymers are useful in the management of tumor therapy to pre- vent tumor recurrence or development of metasteses by an immunoregulatory mechanism. -1-

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