Derivatives of 6-(m-aminophenyl)-2,3,5,6-...

Details Derivatives of 6-(m-aminophenyl)-2,3,5,6-... Derivatives of 6-(m-aminophenyl)-2,3,5,6-...

C - Chemistry, Metallurgy

07

D

260/299

C07D 513/04 (2006.01) C07D 261/18 (2006.01)

Patent

CA 1088546

ABSTRACT OF THE DISCLOSURE The 1- and d1-(racomic) forms of the compounds of the formula: Image ...(I), wherein R is H or CH3, and the non-toxic acid addition salts thereof, useful as antihelmintic compounds are disclosed. The compounds may be prepared by reacting 1- or d1- 6-(m-aminophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole with an acid of the formula: Image ...(III), wherein R is H or CH3, or with its functional equivalent as an acylating agent, and if desired, when the d1- form of the thiazole starting material is used, resolving the d1- product so as to obtain the 1- form, and if desired, converting an 1- or d1- form of a compound of the Formula (I), into a non-toxic addition salt by reaction with a suitable acid.

287801

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