Method for the preparation of biocompatible materials by the...

C - Chemistry – Metallurgy – 12 – N

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167/103.37

C12N 11/00 (2006.01) A61L 33/00 (2006.01)

Patent

CA 1148466

CASE 1240 METHOD FOR THE PREPARATION OF BIOCOMPATIBLE MATERIALS BY THE SUPERFICIAL IMMOBILIZATION OF APYRASE ABSTRACT OF THE DISCOSURE Biocompatible materials are prepared by immobilizing on an appropriate polymer substrate a biologically active agent capable of removing adenosine diphosphate from blood, preferably apyrase, the immobilization being carried out by adsorption and cross-linking procedures or by the formation of a covalent bond between the biologically active agent and certain functional groups of the substrate molecule.

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