Composition having local anesthetic effect

Details Composition having local anesthetic effect Composition having local anesthetic effect

A - Human Necessities

61

K

167/274

A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 47/10 (2006.01)

Patent

CA 1042798

ABSTRACT A local anesthetic composition having the ability to penetrate un- broken skin on topical application and giving a deep and prolonged anesthesia. The composition consists of a solution containing at least 1 % (w/v) of the base form of the compound c-diisopropylaminoethoxybutyrophenone dissolved in a solvent comprising 40-70 % (v/v) isopropanol and 10-60 % (v/v) glycerol. The invention also relates to a method for improving the skin penetrating ability for the base form of the compound o-diisopropylaminoethoxybutyrophen- one by dissolving the compound in a solvent comprising 40-70 % (v/v) isoprop- anol and 10-60 % (v/v) glycerol. The composition of this invention has a more rapid on set and longer duration than known anesthetic compositions.

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