N-hydroxylpropylamides of all-e retinic acid and...

Details N-hydroxylpropylamides of all-e retinic acid and... N-hydroxylpropylamides of all-e retinic acid and...

C - Chemistry, Metallurgy

07

D

260/395.2, 260/3

C07D 319/06 (2006.01) C07D 309/12 (2006.01) C07D 317/28 (2006.01)

Patent

CA 1136638

Abstract of the disclosure: Novel N-hydroxypropyl- amides of all-E-retinic acid and 13-Z-retinlc acid of the general formulae I and II, Image where X and Y are hydrogen or hydroxyl, but at least one is hydroxyl, or X and Y together with the carbon atoms linking them form a 2,2-dimethyl-1,3-dioxolane ring, the preparation of these compounds, pharmaceutical formula- tions containing the compounds and their use as drugs in the topical and systemic therapy and prophylaxis of pre- cancerous conditions and carcinomas and of dermatological disorders.

336668

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