Process for the preparation of tetracyclic indole derivatives

Details Process for the preparation of tetracyclic indole derivatives Process for the preparation of tetracyclic indole derivatives

C - Chemistry, Metallurgy

07

D

260/279, 260/298

C07D 487/04 (2006.01) C07D 487/06 (2006.01)

Patent

CA 1132555

ABSTRACT OF THE DISCLOSURE A process is disclosed for the preparation of a com- pound of formula (I) : (I) Image wherein R1 represents a hydrogen atom, or a carboxy, alkoycar- bonyl, piperidinocarbonyl, 1-pyrrolidinylcarbonyl, morpholinocar- bonyl, carbamoyl or benzylcarbamoyl group, or an alkylcarbamoyl or dialkylcarbamoyl group in which the, or each, alkyl group has from 1 to 4 carbon atoms; R2 represents a hydrogen or fluorine atom, or a cyano, acetyl or carbamoyl group; and R3 represents a hydrogen atom or a metbyl group; and Image represents a single or double bond, with the psoviso that R1 and R2 do not simultaneously represent hydro- gen atoms; or a pharmaceutically acceptable salt thereof.

347558

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