Thiophene compounds

Details Thiophene compounds Thiophene compounds

C - Chemistry, Metallurgy

07

D

260/329.1

C07D 333/36 (2006.01) C07D 333/00 (2006.01) C07D 333/10 (2006.01)

Patent

CA 1101874

RAN 4227/43-1 ABSTRACT The invention relates to compounds of the formula Image I wherein R is aryl, aralkyl, -(CH2)n-R5, and Image , where R5 is hydroxy or Image with R6 being hydrogen, lower alkoxy, amino and R7 is lower alkyl, n is an integer from 1-6, R2 is hydrogen, hydroxy, lower alkoxy, or amino; R3 and R4, which may be the same or different, are lower alkyl, aryl, aralkyl, acyl and hydrogen; and the pharmaceutically acceptable salts thereof, to intermediates for the preparation of these compounds and salts, as well as to a process for the preparation of said compounds, salts and inter- mediates. The compounds of formula I and the salts thereof have antiobesity and blood lipid lowering agents.

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