Process for the preparation of optionally substituted...

C - Chemistry – Metallurgy – 07 – D

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260/242.01

C07D 487/04 (2006.01)

Patent

CA 1055024

A NEW PROCESS FOR THE PREPARATION OF OPTIONALLY SUBSTITUTED 1,2,3,5- TETRAHYDROIMIDAZO[2,1-b]QUINAZOLIN 2-ONES Abstract of the Disclosure A new process has been developed for the synthesis of optionally substituted 1,2,3,5-tetra- hydroimidazo[2,1-b]quinazolin-2-ones. In particular the process is particularly adaptable for the preparation of the 5,6-disubstituted compounds, e.g., 5,6-dimethyl-1,2,3,5-tetrahydroimidazo- [2,1-b]quinazolin-2-one. The compounds so prepared are useful as blood platelet anti-aggregative and/or antihypertensive agents in mammals, including humans.

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