Amino-substituted tetracyclic compounds

Details Amino-substituted tetracyclic compounds Amino-substituted tetracyclic compounds

C - Chemistry, Metallurgy

07

D

260/200.1, 260/2

C07D 223/14 (2006.01) C07D 313/06 (2006.01) C07D 337/06 (2006.01)

Patent

CA 1074305

ABSTRACT OF THE DISCLOSURE This invention relates to a process for the preparation of compounds of the general formula: Image II in which X represents oxygen, sulphur, the group Image or the group -CR8R9-, R1, R2, R3 and R4 represent hydrogen, hydroxy, halogen, alkyl (1-6 C) alkoxy (1-6 C), or trifluoromethyl. R7 stands for hydrogen or alkyl (1-4 C), and R8, R9 stand for hydrogen or methyl, characterized in that a compound of the general formula: Image III is condensed with vinylmethylketone Image . The compounds so produced are useful as intermediates in the synthesis of compounds having useful pharmacological properties.

318926

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