Prostane derivatives

Details Prostane derivatives Prostane derivatives

C - Chemistry, Metallurgy

07

C

260/235.01

C07C 405/00 (2006.01) C07D 305/06 (2006.01) C07D 305/08 (2006.01) C07D 331/04 (2006.01) C07F 9/655 (2006.01)

Patent

CA 1119591

ABSTRACT OF THE DISCLOSURE The disclosure relates to novel .omega.-pentanor prostag- landin E analogs bearing a 4- or 5-membered O or S hetero-ring as 15-substituent, for example 15-(3-butyloxetan-3-yl)-ll.alpha.,15- dihydroxy-9-oxo-16,17,18,19,20-pentanor-5-cis,13-trans-prostadienoic acid, which are useful as inhibitors of gastric acid production in mammals, together with pharmaceutical and veterinary compositions containing such compounds, and a method of using such compounds to inhibit gastric acid production in mammals.

291953

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