Thioalkanoylalkanoic acid compounds

Details Thioalkanoylalkanoic acid compounds Thioalkanoylalkanoic acid compounds

C - Chemistry, Metallurgy

07

C

260/471, 260/486

C07C 61/08 (2006.01) A61K 31/10 (2006.01) A61K 31/19 (2006.01) A61K 31/21 (2006.01) A61K 31/215 (2006.01) A61K 31/265 (2006.01) C07C 59/76 (2006.01) C07C 61/00 (2006.01) C07C 61/16 (2006.01) C07C 69/74 (2006.01) C07D 307/93 (2006.01)

Patent

CA 1125783

ABSTRACT Thioalkanoylalkanoic acid compounds and salts thereof having the formula Image wherein R1, R2, R3 and R4 each is hydrogen or lower alkyl; R5 is hydrogen, lower alkanoyl, benzoyl or Image A and B each is hydrogen or join together as a polymethylene chain -(CH2)n- to complete a 4-, 5- or 6- membered cycloalkyl group, and m is 0 or 1, are angiotensin converting enzyme inhibitors and are useful as hypotensive agents.

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