C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
260/300, 260/335
C07F 3/14 (2006.01) C07F 3/10 (2006.01)
Patent
CA 1086739
ABSTRACT Compounds of the formula Image wherein R1 is lower alkyl, diphenylmethyl, 2,2,2-trichloro- ethyl, p-methoxybenzyl, or p-nitrobenzyl; R2 is hydrogen or acetoxy; R5 is lower alkyl; and R4 is Image , Image , or Image wherein R3 is a heterocyclic qroup, lower alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, phenyl, substituted phenyl, phenyl-lower alkyl, or phenoxy and X is hydrogen, protected amino or pro- tected hydroxy proviaed that X is protected amino or pro- tected hydroxy only when R3 is phenyl, substituted phenyl, or cycloalkadienyl, are disclosed. These compounds are useful as intermediates in the preparation of antibacterially active 2-alkoxy cephalosporins.
264042
Cimarusti Christopher M.
Slusarchyk William A.
E. R. Squibb & Sons Inc.
Osler Hoskin & Harcourt Llp
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