Method for the preparation of apovincamine from vincamine...

Details Method for the preparation of apovincamine from vincamine... Method for the preparation of apovincamine from vincamine...

C - Chemistry, Metallurgy

07

D

260/272

C07D 455/02 (2006.01) C07D 461/00 (2006.01)

Patent

CA 1100135

ABSTRACT A method is disclosed for the preparation of apovinca- mine, a substance being used in the pharmaceutical field as the active ingredient of drugs having cerebral vaso- dilating activity. The method of the invention permits the apovincamine to be directly obtained from vincamine or epivincamine by reaction with a Lewis acid.

308873

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