Ergot peptide alkaloid derivatives

C - Chemistry – Metallurgy – 07 – D

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260/206.3

C07D 519/02 (2006.01) C07D 487/04 (2006.01) C07D 498/14 (2006.01)

Patent

CA 1105007

ERGOT PEPTIDE ALKALOID DERIVATIVES Abstract of the Disclosure Compounds of formula I, Image I wherein R1 is alkyl of 1 to 4 carbon atoms, R2 is hydrogen, alkyl of 1 to 4 carbon atoms or benzyl, R3 and R5 are, independently, hydrogen or methyl, R4 is hydrogen or alkyl of 1 to 4 carbon atoms, and R6 and R7 together form a single bond, or R6 and R7 are each hydrogen, R6 is methoxy, and R7 is hydrogen, are useful in the treatment of hypertension, angina pectoris, depressions, neuroses and psychoses.

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