Process for producing d-penicillamine and preparation...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 31/10 (2006.01) A61K 31/60 (2006.01) C07D 277/06 (2006.01)

Patent

CA 1138776

ABSTRACT OF THE DISCLOSURE D-penicillamine - containing preparations used for trea- ting various diseases, e.g., heavy metal poisoning and Wilson's disease are found to have fewer side effects when only synthetic- ally produced D-penicillamine is used in the preparations. Com- pletely synthetic D-penicillamine can be prepared by the racemate splitting of synthetically produced D, L -penicillamine derivatives using an optically active base, e.g., brucine, 1-norephedrine, 1- ephedrine or d-pseudo-ephedrine.

167082

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