Lipogenesis inhibiting composition and process for its...

A - Human Necessities – 61 – K

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A61K 31/335 (2006.01) C07C 37/055 (2006.01) C07C 41/26 (2006.01) C07C 43/23 (2006.01) C07D 319/20 (2006.01)

Patent

CA 1140856

ABSTRACT Lipogenesis inhibiting composition and process for its preparation This invention relates to lipogenesis inhibiting compositions and their preparation. There are provided lipogenesis inhibiting compositions comprising a pharmaceutically or veterinarily acceptable carrier associated with a benzodioxincarboxylic acid derivative of formula Image (I) where the group CH3-X- is attached at the 5, 6, 7 or 8 - position on the benzodioxin ring system, X is an oxygen atom or a -(CHOH)- group and R is an alkyl group of from 1 to 4 carbon atoms, in a pharmaceutically or veterinarily acceptable state of purity; and the preparation of such compositions. The compositions exhibit a surprisingly effective level of lipogenesis inhibiting activity in mammals.

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