Process for preparation of pyrryl-2-acetonitriles

Details Process for preparation of pyrryl-2-acetonitriles Process for preparation of pyrryl-2-acetonitriles

C - Chemistry, Metallurgy

07

D

260/326

C07D 207/32 (2006.01) C07D 207/337 (2006.01)

Patent

CA 1064507

Abstract of the Disclosure Pyrryl-2-acetonitrile compounds are made by an improved process wherein a dialkyl-(pyrryl-2-methyl)-amine is reacted with an alkyl chloride or alkyl bromide, having up to two carbon atoms in the alkyl, forming a corresponding trialkyl-(pyrryl-2-methyl)-ammonium chloride quaternary salt which solution is then fed to an aqueous solution of alkali cyanide in the presence of a water-immiscible solvent, the alkali cyanide being in defined excess and the reaction being at a controlled temperature level.

252843

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