Suspension of microencapsulated bacampicillin acid addition...

Details Suspension of microencapsulated bacampicillin acid addition... Suspension of microencapsulated bacampicillin acid addition...

A - Human Necessities

61

K

167/169, 167/187

A61K 9/50 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/43 (2006.01)

Patent

CA 1137414

Abstract A novel formulation of bacampicillin for oral administration is disclosed. Microcapsules comprising an acid addition salt of bacampicillin coated with a mixture of ethyl cellulose:water-soluble or water- permeable filler material are suspended in a buffered vehicle having a pH of at least 6.9. The novel suspension is characterized by palatable taste, surprisingly good stability and enhanced bioavailability after oral administration. The novel suspension is well suited for multiple dose oral administration. The preferred filled material is hydroxypropyl cellulose.

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