Process for isolating albumin from blood

Details Process for isolating albumin from blood Process for isolating albumin from blood

A - Human Necessities

61

K

167/103.9

A61K 35/16 (2006.01)

Patent

CA 1038292

ABSTRACT OF THE DISCLOSURE: The extraction of pure serum albumin from blood plasma, blood products, other body fluids or tissue extracts, is effected by separating the plasma from the solid constituents of the blood, isolating dissolved non-albumin-constituents from the plasma, adding an albumin-stabiliser in a quantity of 0.001 to 0.01 moles,treating the fluid with a lower aliphatic alcohol of the formula CH3- (CH2)n- OH in which n is 0,1 or 2 at a temperature of from 60 to 75°C and pH of from 4.5 to 7.5 to cause precipitation of partially or largely denaturated concomitant proteins, the treatment being carried out at a volume concentration of the alcohol of 7 to 14 %, and separating the resultant solution containing pure serum albumin from the precipitate. The process of the invention is applicable to the direct recovery of serum albumin from the plasma with high percentage of yield, high purity making the product applicable to the human body, even for intravenous application.

223373

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