Aminobenzazocines and preparation thereof

Details Aminobenzazocines and preparation thereof Aminobenzazocines and preparation thereof

C - Chemistry, Metallurgy

07

D

260/237.85

C07D 221/26 (2006.01) C07D 221/22 (2006.01)

Patent

CA 1063105

ABSTRACT OF THE DISCLOSURE N-Alkylated-8-aminated-2,6-methano-3-benzazocines,, useful as strong analgesics, are prepared by one route comprising reduction of 8-nitro intermediates or by another route comprising Birch type reduction of 8-methoxy inter- mediates followed by dehydration-rearrangement of the oximes of the resulting 8-oxo intermediates.

235545

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