Method and apparatus for monitoring glucose

Details Method and apparatus for monitoring glucose Method and apparatus for monitoring glucose

G - Physics

01

N

150/14, 73/51.5

G01N 21/64 (2006.01) C12M 1/40 (2006.01) C12Q 1/54 (2006.01)

Patent

CA 1300395

P-933 METHOD AND APPARATUS FOR MONITORING GLUCOSE ABSTRACT OF THE DISCLOSURE A method for monitoring the glucose level in a body fluid uses an apparatus which includes a conjugate of glucose oxidase and a fluorescent dye coated onto an optical fiber in contact with the body fluid, a source of excitation light and a fluorescence emission detector. Glucose is oxidized by oxygen in the body fluid causing a decrease in oxygen concentration at the enzyme. The fluorescent dye is sensitive to oxygen quenching so that, when the oxygen concentration decreases, fluorescence emission increases in direct proportion to the glucose concentration in the fluid.

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