Over-coated chewing gum formulations

Details Over-coated chewing gum formulations Over-coated chewing gum formulations

A - Human Necessities

61

K

A61K 9/68 (2006.01) A23G 4/00 (2006.01) A23G 4/12 (2006.01) A61K 9/24 (2006.01) A61K 31/522 (2006.01)

Patent

CA 2365826

Methods and products for delivering a medicament or agent to an individual are provided. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.

L'invention concerne des méthodes et des produits permettant d'administrer un médicament ou un agent à un sujet. Le produit comprend un enrobage contenant un médicament ou un agent. Ce médicament ou cet agent est présent à l'intérieur de l'enrobage qui entoure le centre d'une gomme (la partie hydrosoluble ou une partie de base insoluble dans l'eau). En mâchant la gomme, le médicament ou l'agent est libéré du produit. En continuant de mâcher la gomme, une pression se crée à l'intérieur de la cavité buccale, poussant l'agent ou le médicament directement dans le système systémique du sujet par le biais de la muqueuse buccale contenue dans ladite cavité. Ceci permet d'améliorer grandement l'absorption du médicament dans le système systémique, ainsi que la biodisponibilité du médicament dans le système.

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