Compounds and methods for modulating functions of classical...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 14/705 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07D 211/58 (2006.01) C07K 5/103 (2006.01) C07K 5/113 (2006.01) C07K 5/117 (2006.01) C07K 7/04 (2006.01) C07K 7/64 (2006.01) C07K 16/28 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2504768

Modulating agents and methods for enhancing or inhibiting classical cadherin- mediated functions are provided. The modulating agents comprise at least a tryptophan-containing cell adhesion recognition sequence of a classical cadherin molecule, a conservative analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a cell adhesion recognition sequence. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, pharmaceutically active substance and/or support material.

L'invention concerne des agents et des procédés de modulation permettant d'améliorer ou d'inhiber des fonctions régulées par des cadhérines classiques. Ces agents de modulation comprennent au moins une séquence de reconnaissance d'adhésion de cellules contenant tryptophane d'une molécule de cadhérine classique, un analogue conservatif ou un peptidomimétique de cette séquence, ou un anticorps ou un fragment d'anticorps de cette séquence qui se lie spécifiquement à cette séquence de reconnaissance d'adhésion de cellules. Des agents de modulation peuvent comprendre en plus une ou plusieurs séquences de reconnaissance d'adhésion de cellules reconnues par les cadhérines et/ou par d'autres molécules d'adhésion. Ces agents de modulation peuvent, éventuellement, être liés à un agent de ciblage, à une substance pharmaceutiquement active et/ou à une matière de support.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Compounds and methods for modulating functions of classical... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds and methods for modulating functions of classical..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and methods for modulating functions of classical... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1342357

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.