Replication incompetent herpes virus vectors

Details Replication incompetent herpes virus vectors Replication incompetent herpes virus vectors

C - Chemistry, Metallurgy

12

N

C12N 15/869 (2006.01) A61K 48/00 (2006.01) C12N 7/04 (2006.01)

Patent

CA 2395578

Use replication incompetent herpes virus comprising a heterologous gene in the manufacture of a medicament for use in treating or preventing a peripheral nervous system disorder by administering said medicament to a peripheral nerve, in a method of determining whether a gene has an effect on a phenotype associated with a peripheral nervous system disorder and in a method of treatment of a disorder of the peripheral nervous system.

La présente invention concerne l'utilisation d'une réplique d'herpèsvirus atténué comprenant un gène hétérologue pour la fabrication d'un médicament destiné au traitement ou à la prévention d'un trouble du système nerveux périphérique. Pour ce traitement, on administre à un nerf périphérique ce médicament. L'invention concerne également un procédé permettant de vérifier si un gène a un effet sur un phénotype associé à un trouble du système nerveux périphérique. L'invention concerne enfin un procédé se rapportant au traitement d'un trouble du système nerveux périphérique.

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