A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 25/02 (2006.01) A61B 17/22 (2006.01) A61K 9/00 (2006.01) A61K 48/00 (2006.01) A61L 29/16 (2006.01) A61M 25/10 (2006.01)
Patent
CA 2112375
2112375 9300052 PCTABS00019 A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
Nabel Elizabeth G.
Nabel Gary J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Regents Of The University Of Michigan
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