Conjugates of soluble t4 proteins and toxins and methods for...

Details Conjugates of soluble t4 proteins and toxins and methods for... Conjugates of soluble t4 proteins and toxins and methods for...

C - Chemistry, Metallurgy

12

N

530/13, 167/130,

C12N 15/62 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01) C07K 14/21 (2006.01) C07K 14/73 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2000989

ABSTRACT This invention relates to compositions and methods useful for the treatment and prevention of acquired immunodeficiency syndromes (AIDS), AIDS related complex (ARC), and human immunodeficiency virus (HIV) infection. More particularly, this invention relates to immunotoxins formed by conjugating a toxin to a soluble T4 protein, an HIV virus receptor that binds to the HIV virus or to target cell carrying the gp120/160 HIV marker. This invention also relates to methods for secreting soluble T4-toxin fusion protein conjugates through the cell membrane of a host. The compositions and methods of this invention advantageously provide a highly specific, site-directed delivery system for delivery of toxin to HIV infected cells and to circu- lating HIV virus.

Affiliated with

Also associated with

Rating

Conjugates of soluble t4 proteins and toxins and methods for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates of soluble t4 proteins and toxins and methods for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates of soluble t4 proteins and toxins and methods for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1428113