Enzymatically synthesized marine phospholipids

A - Human Necessities – 23 – J

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A23J 7/00 (2006.01) C11C 3/08 (2006.01)

Patent

CA 2587730

This invention discloses an improved enzymatic process, under organic solvent free conditions, for the incorporation of fatty acids such as omega-3 fatty acids into phospholipids. The rate of transesterification is increased 4 times by adding a base to the reaction mixture, typically an amine. The invention also discloses novel phospholipid compositions as well as novel use of the phospholipid compositions as a food supplement, a fish feed, animal feed and human food. In addition to methods for enriching prey organisms used in aquaculture, methods of reducing arachidonic acid levels in mammalian plasma/red blood cells and methods for increasing DHA levels in the mammalian brain.

La présente invention se rapporte à un processus enzymatique amélioré, mis en oeuvre dans des conditions exemptes de solvant organique, qui est destiné à incorporer des acides gras tels que des acides gras oméga-3 dans des phospholipides. Le taux de transestérification est multiplié par quatre lorsque l'on ajoute une base au mélange réactionnel, en général une amine. L'invention a également trait à de nouvelles compositions phospholipidiques, ainsi qu'à une nouvelle utilisation desdites compositions phospholipidiques en tant que complément alimentaire, aliment pour poissons, aliment pour animaux et aliment destiné à la consommation humaine. L'invention concerne, outre des procédés d'enrichissement d'organismes proies utilisés en aquaculture, des procédés permettant de réduire les niveaux d'acide arachidonique dans le plasma ou les globules rouges de mammifères, ainsi que des procédés permettant d'augmenter les niveaux de DHA dans le cerveau de mammifères.

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