C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/352 (2006.01) A61P 35/00 (2006.01) C07D 311/94 (2006.01) C07D 493/04 (2006.01)
Patent
CA 2518819
This invention relates to novel heterocycles which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), also referred to as 11CBy, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in medicines. Compounds of the invention have the formula: (I)
La présente invention concerne de nouveaux dérivés de benzopyrane substitués, des stéréoisomères et des sels pharmaceutiquement acceptables de ceux-ci, ainsi que des procédés pour les préparer. Les composés de l'invention sont utiles en tant qu'agonistes du récepteur .beta. de l'oestrogène. De tels agonistes sont utiles pour traiter des maladies liées au récepteur .beta. de l'oestrogène telles que le cancer de la prostate ou BPH.
Durst Gregory Lee
Norman Bryan Hurst
Pfeifer Lance Allen
Richardson Timothy Ivo
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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