Self micro-emulsifying oral pharmaceutical composition of...

Details Self micro-emulsifying oral pharmaceutical composition of... Self micro-emulsifying oral pharmaceutical composition of...

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 31/4184 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2760039

A self micro-emulsifying oral pharmaceutical composition of hydrophilic drug or its pharmaceutical acceptable salt and the preparation method thereof are disclosed. The composition comprises hydrophilic drug such as bendamustine or gemcitabine, solvent, surfactant and hydrophilic carrier, and has good bioavailability and stability. Said hydrophilic carrier is compatible with drug solution and surfactant.

L'invention porte sur une composition pharmaceutique orale auto-micro-émulsifiante de médicament pharmaceutique ou sur son sel pharmaceutiquement acceptable et sur son procédé de préparation. La composition comprend un médicament hydrophile tel que la bendamustine ou la gemcitabine, un solvant, un agent tensio-actif et un support hydrophile, et a une bonne biodisponibilité et une bonne stabilité. Ledit support hydrophile est compatible avec la solution de médicament et l'agent tensio-actif.

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