Solid compositions suitable for oral administration...

Details Solid compositions suitable for oral administration... Solid compositions suitable for oral administration...

C - Chemistry, Metallurgy

07

C

C07C 229/22 (2006.01) A23L 1/305 (2006.01) A23L 1/308 (2006.01) A61K 31/205 (2006.01) A61P 9/00 (2006.01) C07C 229/08 (2006.01) C07C 309/14 (2006.01)

Patent

CA 2427482

Described herein are both non-hydroscopic salts of L-carnitine and alkanoyl L-carnitine with taurine chloride (2-aminoethane-sulphonic chloride) which lend themselves favourably to the preparation of solid compositions suitable for oral administration. Also described are solid compositions containing the salts. The salts are of the general formula (I): (see formula I) wherein R is H or a straight or branched lower alkanoyl with 2-5 carbon atoms.

L'invention porte sur des sels non hygroscopiques de L-carnitine et alcanoyl L-carnitine comprenant un chlorure de taurine (chlorure 2-aminoéthane-sulphonique) et sur des sels non hygroscopiques de L-carnitine et alcanoyl L-carnitine comprenant un chlorure de glycine qui se prêtent particulièrement bien à la préparation de compositions solides appropriées pour être administrées par voie orale. L'invention porte également sur des compositions solides contenant ces sels.

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