Novel polyene antibiotics, 3874 h1 to h6, processes for...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) C07H 17/08 (2006.01) C07H 19/01 (2006.01) C12P 17/18 (2006.01) C12P 19/62 (2006.01)

Patent

CA 2213285

Novel polyene antibiotics, 3874 H1 to H6, processes for their preparation and use Compounds of the formulae 3874 H1, molecular formula C58H86N2O18, MW 1099.3 (see fig. I) 3874 H2, molecular formula: C59H88N2O18, MW 1113.3 (see fig. II) 3874 H3, molecular formula: C57H87NO18, MW 1074.3 (see fig. III) 3874 H4, molecular formula: C58H84N2O18, MW 1097.3 3874 H5, molecular formula: C59H86N2O18, MW 1111.3 3874 H6, molecular formula: C57H85NO18, MW 1072.3 are suitable for treating fungal diseases and for treating diseases associated with an increased steroid concentration.

Nouveaux antibiotiques polyéniques, 3874 H1 à H6, procédés de préparation et utilisation. Les composés de formules 3874 H1, formule moléculaire C58H86N2O18, PM 1099,3 (voir fig. I) 3874 H2, formule moléculaire : C59H88N2O18, PM 1113,3 (voir fig. II) 3874 H3, formule moléculaire : C57H87NO18, PM 1074,3 (voir fig. III) 3874 H4, formule moléculaire : C58H84N2O18, PM 1097,3 3874 H5, formule moléculaire : C59H86N2O18, PM 1111,3 3874 H6, formule moléculaire : C57H85NO18, PM 1072,3; ces composés conviennent au traitement des maladies fongiques et des maladies liées à une concentration accrue de stéroïdes.

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